可的?– 有机?/title> <atom:link href="//9my.com.cn/archives/tag/%E5%8F%AF%E7%9A%84%E6%9D%BE/feed" rel="self" type="application/rss+xml" /> <link>//9my.com.cn</link> <description>有机?/description> <lastBuildDate>Tue, 22 Oct 2024 08:13:28 +0000</lastBuildDate> <language>zh-CN</language> <sy:updatePeriod>hourly</sy:updatePeriod> <sy:updateFrequency>1</sy:updateFrequency> <generator>//wordpress.org/?v=4.9.26</generator> <item> <title>可的?/title> <link>//9my.com.cn/archives/613</link> <pubDate>Tue, 11 Jun 2024 03:27:23 +0000</pubDate> <dc:creator><![CDATA[admin]]></dc:creator> <category><![CDATA[新闻中心]]></category> <category><![CDATA[可的松]]></category> <guid isPermaLink="false">//9my.com.cn/archives/613</guid> <description><![CDATA[l构?物竞~号 015V 分子?C21H28O5 分子?360.44 标签 11-脱氢-17-皮质酮, 肾上腺皮质激? 17,21-Dihydroxy-4-pregnene-3,11,20-trione, 4-Pregnene-17,21-diol-3,11,20-trione, 医药用药 ~号pȝ 物?...]]></description> <content:encoded><![CDATA[<p> <img src="//staticv5.basechem.org/img/tupu/old/7bcbb1871a5247e783137dfe5ea53598.gif" alt="可的杄构式"></p> <p>l构?/p> <table class="summary-table table table-striped table-bordered"> <col width="90" /> <tbody> <tr> <th scope="row">物竞~号</th> <td>015V</td> </tr> <tr> <th scope="row">分子?/th> <td>C21H28O5</td> </tr> <tr> <th scope="row">分子?/th> <td>360.44</td> </tr> <tr> <th scope="row">标签</th> <td> <p> 11-脱(bian)-17-皮质酮,</p> <p> 肾上(guan)皮(xiao)质激?</p> <p>  17,21-Dihydroxy-4-pregnene-3,11,20-trione,</p> <p>  4-Pregnene-17,21-diol-3,11,20-trione,</p> <p> 医药用药</p> </td> </tr> </tbody> </table> <ul class="nav nav-tabs"> <li class="active"><a href="#bh">~号pȝ</a></li> <li><a href="#wx">物性数?/a></li> <li><a href="#dl">毒理学数?/a></li> <li><a href="#st">生态学数据</a></li> <li><a href="#fz">分子l构数据</a></li> <li><a href="#js">计算化学数据</a></li> <li class="dropdown pull-right"> <a href="" class="dropdown-toggle">更多 <span class="caret"></span></a></p> <ul class="dropdown-menu" role="menu"> <li><a href="#xz">性质与稳定?/a></li> <li><a href="#zc">贮存Ҏ</a></li> <li><a href="#hc">合成Ҏ</a></li> <li><a href="#yt">用?/a></li> </ul> </li> </ul> <h2 id="bh">~号pȝ</h2> <p><b>CASP</b>53-06-5</p> <p><b>MDLP</b>MFCD00003610</p> <p><b>EINECSP</b>200-162-4</p> <p><b>RTECSP</b>GM9020000</p> <p><b>BRNP</b>1356062</p> <p><b>PubChemP</b>24278304</p> <h2 id="wx">物性数?/h2> <p><p>1.       性状Q?nbsp; 白色l晶性粉末。系肾上腺的分泌物?/p> <p>2.       密度Qg/mL,25/4℃）Q?未确?/p> <p>3.       相对蒸汽密度Qg/mL,I气=1Q：未确?/p> <p>4.       熔点QºCQ：  220?24℃（部分分解Q?/p> <p>5.       沸点QºC,常压Q：未确?/p> <p>6.       沸点QºC,5.2kPaQ：未确?/p> <p>7.       折射率：未确?/p> <p>8.       闪点QºCQ：未确?/p> <p>9.       比旋光度Qº）Q[]D25 +209QC=1.2Q?5%中）Q[]54625 +269QC=0.125Q中Q?/p> <p>10.    自燃Ҏ引燃温度QºCQ：未确?/p> <p>11.    蒸气压（kPa,25ºCQ：未确?/p> <p>12.    饱和蒸气压（kPa,60ºCQ：未确?/p> <p>13.    燃烧热（KJ/molQ：未确?/p> <p>14.    临界温度QºCQ：未确?/p> <p>15.    临界压力QKPaQ：未确?/p> <p>16.    ҎQ辛?_分配pL的对数|未确?/p> <p>17.    爆炸上限Q?,V/VQ：未确?/p> <p>18.    爆炸下限Q?,V/VQ：未确?/p> <p>19.    溶解(hao)：  溶(duo)、(heng)酮、和L醇(jun)极少(gan)溶(duo)、和氯仿Q微(jing)溶(duo)_(da)25，28mg/100mlQ，水(cun)液呈中性。在(pu)呈深U色溶液(dong)Qƈ(lian)深l(zi)色荧光。加(jie)能q(ma)原(lian)尼q(ma)特QBenedict’sQ溶涌Ӏ?/p> </p> <h2 id="dl">毒理学数?/h2> <p> 暂无 </p> <h2 id="st">生态学数据</h2> <p> 暂无 </p> <h2 id="fz">分子l构数据</h2> <p><p>1?nbsp;  摩尔折(hua)率：94.17</p> <p>2?nbsp;  摩尔体积Qcm<sup>3</sup>/molQ(duo)280.3</p> <p>3?nbsp;  {(jiang)张(jiao)容(90.2K)Q?69.4</p> <p>4?nbsp;  表面(kui)(liao)力(dyne/cm)Q?6.7</p> <p>5?nbsp;  极化?10-24cm<sup>3</sup>)Q?7.33</p> </p> <h2 id="js">计算化学数据</h2> <p><p>1?nbsp;  (ding)水参(yong)(kai)(cong)算参(ta)|XlogPQ(duo)1.5</p> <p>2?nbsp;  氢键(zhu)(shui)(hong)数量Q?</p> <p>3?nbsp;  氢键受体数量()Q(ben)?</p> <p>4?nbsp;  可旋转化学键数量Q(ben)?</p> <p>5(mo)?nbsp;  互变异构(ying)体数(kai)量：45</p> <p>6?nbsp;  拓扑(rou)子极性表面积QTPSAQ(duo)(xi)91.7</p> <p>7?nbsp;  (yue)原(ying)数(yue)：26</p> <p>8?nbsp;  表面电(dian)Q?</p> <p>9?nbsp;  复杂(qian)：(xi)724</p> <p>10、同(huan)(qu)原子(suo)量Q?</p> <p>11(mo)确定原子立(man)中心数量：6</p> <p>12、不(zhen)定原子立()中心数量Q?</p> <p>13、确定(ya)学键立()中心(suo)量()Q?</p> <p>14(mo)不(yun)定化学键立(man)(qiao)(fu)心数量：0</p> <p>15、(huo)价键单元(suo)量Q?</p> </p> <h2 id="xz">性质与稳定?/h2> <p><p>(ning)温(fu)(ning)压下性质E_</p> </p> <h2 id="zc">贮存Ҏ</h2> <p><p>本品(qian)(you)于(lu)阴凉q燥处保存(pu)?/p> </p> <h2 id="hc">合成Ҏ</h2> <p> <span style="font-family:宋(yu)(hong);font-size:x-small;color:#333333">1.可由(ai)(xiang)上腺提取液分(pang)Q()(shan)可由(ai)(jian)汁(tong)(yan)、山(bei)药皂草(ling)(chu)为原料(luo)得?span lang="EN-US"></span></span> </p> <h2 id="yt">用?/h2> <p><p>1.主要用于肾上腺皮质功能减退症的替代ȝQ但现在氢化可的村ַ优先用于此症。因为可的松本n无活性，必需先在肝内转化成氢化可的松Q某些肝脏疾病将影响其作用的可靠性?/p> <p>2.<span style="font-family:Arial">药用(ke)(tuan)(jiao)皮肤(chun)吸收Q用(ke)于急、慢性湿疹，瘙(zan)症(jiong)各种皮炎的理疗(yan)也(mei)用于(lu)化妆水、^(gou)膏和(nin)生发水(cui)Q()(zhang)节体内电(dian)(lu)和(nin)水的q、糖和()白质的代(zhang)等功(xi)。有(shi)抗炎症、抗q敏症(jiong)(nin)抗(bian)(gan)(qu)等功效(han)?/span></p> </p> <p> 扩展阅读<a 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